The effect of hypertonic glucose infusion on dialysis adequacy in non-diabetic hemodialysis patients
Journal of Critical Care Nursing : August 31, 2006,
5 (4); e7069
October 30, 2012
Article Type: Research Article
August 27, 2016
April 23, 2012
S , Tadrisi
S D , Sadeghi Sherme
M , Einollahi
B , Tayebi
A . et al. The effect of hypertonic glucose infusion on dialysis adequacy in non-diabetic hemodialysis patients,
Crit Care Nurs J.
Aims: Hemodialysis Patients suffer from many problems and complications
during disease and their treatment. One of the most important and common
problems is hypotension and dialysis adequacy. This study has been designed
and implemented to determine the effect of hypertonic glucose on dialysis
adequacy and blood pressure in non-diabetic dialysis patients.
Methods: The present study was a quasi-experimental and single group study
that 45 none-diabetic hemodialysis patients from the chosen hospitals were
selected and hypertonic glucose infused patients for two weeks and three
times a week, after two weeks durability, patients were assessed without
manipulation for two weeks. In addition blood pressure and dialysis adequacy
of the patients were measured in manipulation phase before and after each
infusion of hypertonic glucose .Data collection tools included demographic
information and dialysis adequacy was calculated by Daugirdas formula at the
end of every stage in two study environments. Then the data were analyzed by
using SPSS 17 software and descriptive statistical tests (abundance- mean),
inferential tests (paired t test, mane Whitney, Friedman, Kruskal-wallis and
Results: The results showed that dialysis adequacy and also blood pressure of
the patients had been increased significantly in manipulation phase (p=0.001).
And analysis of data between the gender (p=0.001) and vascular access
(p=0.001) showed significant differences (p=0.001),but in other cases, there
was no significant difference.
Conclusion: results of this study showed that injection of hypertonic glucose
increased dialysis adequacy in hemodialysis patients significantly and
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